Process Optimization for Aqueous Ethanosolv Pretreatment of Coffee Husk Biomass Using Response Surface Methodology

This study targeted to optimize process factors using response surface methodology and determining their effect on delignification cellulose recovery. Optimization of pretreatment conditions with desirability value 0.828 was done at temperature (A) 150°C, contact time (B) 2 h, liquid-to-solid ratio (LSR) (C) 15 ml/g. The sample soaked in an aqueous ethanol solution (48% ethanol). Chemical composition determined be 1.87 ± 0.20, 7.03 0.99, 28.05 0.27, 39.29 3.39, 23.77 3.91 wt% for ash, extractives, lignin, hemicellulose, cellulose, respectively. Experimental results were validated by comparing actual predicted value. model verified as the best improving yield. Coefficient determination (R2), analysis variance (ANOVA), plots, optimization nodes used examine experimental results. quadratic equation test model, ANOVA evaluate model’s statistical performance correctness. Temperature, interaction term (BC), terms (A2, B2, C2) showed significance, while time, LSR, (AC AB) indicated insignificance (AB), (B2 but BC), (A2) delignification. Pretreatment efficacy (6.0%) recovery (151.80%) achieved optimal conditions. method is able produce cellulose-rich coffee husk residues.